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Jennifer Aniston, 50 Cent

Matthew Broderick, Teri Garr

Kelly Ripa, Hilary Duff

Steve Martin, the Teutul family from "American Chopper"

Ted Koppel, Jim Gaffigan, Trey Anastasio

Kid scientists, John Cusack

Joaquin Phoenix, Trisha Yearwood

Ellen DeGeneres, Brad Paisley

Howard Stern, Pharrell Williams

Sen. John McCain, Carla Gugino

George Clooney, Ashlee Simpson

Dennis Quaid, Donovan McNabb

Stupid Pet Tricks, Claire Danes, Big Boi

Megan Mullally, John Mayer Trio

John Malkovich, NASCAR Nextel Cup winner, Jim Gaffigan

Stupid Human Tricks, Amanda Peet

Regis Philbin, Colin Hanks

Charlize Theron, Maureen Dowd

Oprah Winfrey, Bonnie Raitt

Rodeo champion Billy Etbauer

Jack Black, Reggie Bush, Sinead O'Connor

Sarah Jessica Parker, John Witherspoon

Stephen Colbert, Aqualung

Alec Baldwin, Shakira

Dr. Phil McGraw, Bill Scheft

Jim Carrey, We Are Scientists

Bonnie Hunt, Stephen A. Smith

Nathan Lane, Tom Dreesen

Jamie Foxx, Andy Kindler

Rosie Perez, Jay Thomas, Darlene Love

Heather Graham, Fall Out Boy

Bill O'Reilly, Eric Bana

Pierce Brosnan, Marv Albert

Felicity Huffman, David Rakoff, Common

Amy Sedaris, Dennis Regan, the Temptations

Albert Brooks, Kristin Cavallari

Scarlett Johannsen, Tiki Barber, Imogen Heap

Queen Latifah, Bob Sarlatte

Kiefer Sutherland, Alicia Keys, Andy Samberg

Tom Cavanagh, Jake Johannsen

Martin Lawrence, Kari Byron, Matisyahu

Tatum O'Neal, Jeff MacGregor

Kate Beckinsale, Bob Saget

Cheryl Hines, Anna Nalick, Mike Vanderjagt

Charles Grodin, Jordana Brewster

Anthony Hopkins

Bernie Mac, Beth Orton

Mischa Barton, Jeff Altman, Wicked Wisdom

Tommy Lee Jones, Anthony Hamilton

P Diddy, Train

Harrison Ford, Michael Bublé

Beyonce Knowles, Stephen A. Smith

Rachel Weisz, Beastie Boys

Senator John McCain, Heidi Klum

Martha Stewart, Michael Bublé

Geena Davis, INXS

Julianne Moore, Randy Jackson, The O'Jays

Charles Barkley, Catherine Keener

Jimmy Fallon, Hannah Teter, She Wants Revenge

Donald Trump, Bill Burr

Season 13

Episode 149

Talk

Comedy

Late Show with David Letterman

Season 1

Season 2

Season 3

Season 4

Season 5

Season 6

Season 7

Season 8

Season 9

Season 10

Season 11

Season 12

Season 14

Season 15

Season 16

Season 17

Season 18

Season 19

Season 20

Season 21

Season 22

Late Show with David Letterman is an American late-night talk show hosted by David Letterman on CBS. The show debuted on August 30, 1993, and is produced by Letterman's production company, Worldwide Pants Incorporated and CBS Television Studios. The show's music director and band-leader of the house band, the CBS Orchestra, is Paul Shaffer. The head writer is Matt Roberts and the announcer is Alan Kalter. Of the major U.S. late-night programs, Late Show ranks second in cumulative average viewers over time and third in number of episodes over time. The show leads other late night shows in ad revenue with $271 million in 2009.

In most U.S. markets the show airs at 11:35 p.m. Eastern/Pacific time, but is recorded Monday through Wednesday at 4:30 p.m., and Thursdays at 3:30 p.m and 6:00 p.m. The second Thursday episode usually airs on Friday of that week.

In 2002, Late Show with David Letterman was ranked No. 7 on TV Guide's 50 Greatest TV Shows of All Time. CBS has a contract with Worldwide Pants to continue the show through 2014; by then, Letterman will surpass Johnny Carson as the longest tenured late-night talk show host.