Bill Murray, Tom Brokaw, Paul Newman, Billy Joel

Robin Williams, John Mellencamp, Jonathan Estrata

Demi Moore, Bev Tanner, Spin Doctors

Martin Short, Cyndi Lauper

Debra Winger, Soul Asylum

Richard Lewis, Shawn Bouroughs, Midnight Oil

Michael J. Fox, Rosie Perez

Al Gore, Kim Basinger, Chris Isaak

Ellen Barkin, Chris "Mad Dog" Russo, Lenny Kravitz

Siskel & Ebert, Robert Plant

Bruce Willis, Steven Wright

Paul Reiser, Mike Ditka, John Hiatt

Jeff Goldblum, Louie Anderson, Jerry Garcia & David Grisman

Bonnie Hunt, Latrisha Baldrick, Patti Smyth

Super Dave Osborne, Laura Dern, Stone Temple Pilots

Sarah Jessica Parker, Jim Abbot, Patty Scialfa

Robert Urich, Ellen Degeneres, Tim Tomasic

Tony Randall, Elizabeth Perkins, Aaron Neville

Mike Myers, John Kruk, Belinda Carlisle

Glenn Close, James Taylor

Matthew Broderick, Julie Krone, Neil Diamond

Jimmy Carter, Brett Butler, Daniel Boulud

Jerry Lewis, Sparky Mortimer, Rod Stewart

Lily Tomlin, Adam Sandler, Mike Lupica

Andie MacDowell, Graham Parker, Bill Scheft

Sylvester Stallone, Melissa Etheridge, Janeane Garofalo

Isabella Rossellini, Bob Saget, Johnny Cash

Candice Bergen, John Mendoza

Don Rickles, Tracey Ullman, Johnny Cash

Connie Chung, Mary Chapin Carpenter

Kathie Lee Gifford, Matt Dillon

Stupid Pet Tricks, Howard Stern, Rosanne Cash

Kirstie Alley, Rick Ocasek, Jeff Colton

David Brenner, Gloria Estefan, Sean Young

Tom Arnold, Rich Hall, Jon Weiss

Dennis Miller, Tony Bennett, Sandra Bullock

David Steinberg, Emmylou Harris, Bo Jackson

Dan Rather, Penelope Ann Miller, Gin Blossoms

Bob Newhart, Guru, Chloe Disker

Martin Mull, The Pogues, Jean Louie

Sean Connery, Jake Johannsen, Fran Drescher

Phil Donahue, Art Garfunkel, Lenny Dykstra, Paul Molitor

Marv Albert, Cindy Crawford, Natalie Cole

George Foreman, INXS & Ray Charles

Martin Lawrence, Phil Collins

Jay Thomas, Squeeze, Martha Stewart

Terry Garr, Paul Simon

Mike Wallace, Jimmy Cliff, Faith Ford

Annie Potts, Natalie Merchant, Dorothy Nash

Tony Curtis, The Breeders, Calvin Trillian

Michael Keaton, Barbara Walters

Evander Holyfield, Phil Hartman, The BoDeans

Mary Tyler Moore, Jackson Browne, Rita Rudner

Tom Selleck, Pete Townsend

Barry Bonds, Carol Kane, Living Colour

Sinbad, Trisha Yearwood, Charlie Sheen

Billy Crystal, Los Lobos

Stupid Human Tricks, Jon Lovitz, George Thoroughgood

Billy Connolly, Bob Dylan, Charles Kuralt

Dana Carvey, Meatloaf, Joan Cusak

Marilu Henner, Heart, Father Guido Sarducci

Robert Klein, Cowboy Junkies, Bobby Knight

Bryant Gumbel, Taylor Dayne, Dave Attel

Penn & Teller, Dwight Yoakam, Gabriel Byrne

Kelsey Grammar, Patrick Ewing, Warren Zevon

James Belushi, Carlene Carter, Lauren Holley

Robin Williams, Larry Johnson

Sam Donaldson, Mike Myers, Nanci Griffith

Jeremy Irons, Bruce Hornsby

Charles Grodin, Bryan Adams, Jack Hannah

Sally Field, Carly Simon, Robert Duvall

Larry King, The Band, Kevin Pollack

Luciano Pavarotti, Marisa Tomei, Wayne Cotter

Tom Hanks, Gipsy Kings, Joan Plowright

Rush Limbaugh, Harry Connick Jr.

Whoopi Goldberg, Clint Black, John Witherspoon

Will Smith, The Lemonheads, Emmit Smith

Bob Costas, Toni Braxton, Debi Mazar

Dennis Franz, Mike Judge, Andy Williams

Joan Lunden, Ian Moore, Wendy Wasserstein

Jason Priestly, Terry Bradshaw, Norm MacDonald

Bonnie Hunt, Tony Toni Tone, Dennis Rogers

Julia Roberts, Cracker, Wolfgang Puck

Rosanne and Tom Arnold, Jon Bon Jovi

Jane Pauley, Art Donavan

Beau Bridges, Sandra Bernhard, 4 Non Blondes

Rosie O'Donnell, Lou Reed, Neil Patrick Harris

Chris Elliot, Itzhak Perlman, Cokie Roberts

Martin Mull, Drew Carey, Dana Delaney

Rudolph Giuliani, Faith Hill, Ricki Lake

Troy Aikman, Marilyn Horne, Jon Stewart

Smothers Brothers, Indigo Girls, Sara McClendan

George Carlin, Urge Overkill, Jan Hooks

Chevy Chase, George Miller, Halle Berry

Richard Harris, Taj Mahal & Etta James, David Spade

David Brenner, Travis Tritt, Madeline Stowe

Kathie Lee Gifford, Aaron Neville, Bruno Kirby

Demi Moore, Willie Nelson & Shelby Lynne, Al Franken

Dan Rather, Dave Pirner & Victoria Williams, Brett Hull

Jimmy Johnson, Martin Lawrence, Concrete Blonde

Season 1

Episode 149

Talk

Comedy

Late Show with David Letterman

Season 2

Season 3

Season 4

Season 5

Season 6

Season 7

Season 8

Season 9

Season 10

Season 11

Season 12

Season 13

Season 14

Season 15

Season 16

Season 17

Season 18

Season 19

Season 20

Season 21

Season 22

Late Show with David Letterman is an American late-night talk show hosted by David Letterman on CBS. The show debuted on August 30, 1993, and is produced by Letterman's production company, Worldwide Pants Incorporated and CBS Television Studios. The show's music director and band-leader of the house band, the CBS Orchestra, is Paul Shaffer. The head writer is Matt Roberts and the announcer is Alan Kalter. Of the major U.S. late-night programs, Late Show ranks second in cumulative average viewers over time and third in number of episodes over time. The show leads other late night shows in ad revenue with $271 million in 2009.

In most U.S. markets the show airs at 11:35 p.m. Eastern/Pacific time, but is recorded Monday through Wednesday at 4:30 p.m., and Thursdays at 3:30 p.m and 6:00 p.m. The second Thursday episode usually airs on Friday of that week.

In 2002, Late Show with David Letterman was ranked No. 7 on TV Guide's 50 Greatest TV Shows of All Time. CBS has a contract with Worldwide Pants to continue the show through 2014; by then, Letterman will surpass Johnny Carson as the longest tenured late-night talk show host.